Publications-35
| The clinical characteristics of Kleine–Levin syndrome according to ethnicity and geographic location. | |
|
Abstract: Purpose: Kleine–Levin syndrome (KLS) is a rare, relapsing-remitting, debilitating sleep disorder. Examining KLS characteristics in different ethnic populations may help elucidate the genetic basis of the disorder. No studies have examined KLS in Arabs. Therefore, we compared the clinical characteristics of Saudi Arabian KLS patients to those in other published cohorts to determine whether Arab patients have a distinct phenotype...
|
| Insomnia in primary care settings: Still overlooked and undertreated?. | |
|
 |
Abstract: Background: Insomnia is a major medical problem that is often associated with low health status and increased health-care utilization. Therefore, we conducted this study to determine the frequency of insomnia in a population presenting to the primary healthcare (PHC) clinics for health problems other than sleep disorders...| Poor sleep in concurrent users of alcohol, khat, and tobacco smoking in community-dwelling Ethiopian adults. | |
|
Abstract: BACKGROUND: Polysubstance dependence, stress, and sleep disturbances are inter-related by shared physiological pathways. No study has investigated the relationship between sleep and concurrent use of alcohol and khat. OBJECTIVES: The aim of the study was to assess the effect of the concurrent use of alcohol and khat as well as concurrent alcohol, khat, and tobacco smoking on sleep patterns...
|
| A snoring man with an abnormal sexual behavior during sleep. | |
|
|
| The association of BDNF gene polymorphism with cognitive impairment in insomnia patients. | |
|
Abstract: Background: Reductions in BDNF activity have shown associations with depressed mood. Other evidence has demonstrated that the BDNF Val66Met polymorphism (rs6265) appears to reduce neural plasticity. A limited number of studies have investigated the influence of these genetic polymorphisms in insomnia. The present study sought to confirm the presence of associations between BDNF Val66Met polymorphism (rs6265) occurrence in normal sleepers... |
| Body composition, resting metabolic rate, and respiratory quotient in patients with narcolepsy vs BMI-matched controls. | |
|
Abstract: Rationale: Loss of hypocretin neurons in narcolepsy may affect body composition and energy expenditure. The inflammatory basis of narcolepsy is recently suggested1. So, we measured body composition, resting metabolic rate (RMR), respiratory quotient (RQ), and C-reactive protein (CRP) in patients with narcolepsy. Methods: A total of 14 male patients with narcolepsy and 15 male healthy subjects of similar BMI and age were enrolled in a case-control study,...
|
| The effect of caffeine on patients with narcolepsy, in King Khalid Hospital, King Saud University Medical City, Riyadh, Saudi Arabia. | |
|
|
| The characteristics of dental occlusion in patients with moderate to severe obstructive sleep apnea in Saudi Arabia. | |
|
|
Abstract: Objectives: To evaluate characteristics of dental occlusion among non-obese Saudi adult patients suffering from moderate to severe obstructive sleep apnea(OSA). Methods: Following ethical approval, a cross-sectional study was conducted at Sleep Disorders Center, King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia, between January and March 2017. Non-obese adult Saudi patients with moderate/severe OSA (apnea-hypopnea index more than 15) and without history of malocclusion or edentulism were included with an estimated sample size of 50...| Kleine-Levin syndrome is associated with LMOD3 variants. | |
|
Abstract: Kleine-Levin syndrome (KLS) is a rare periodic hypersomnia with associated behavioural abnormalities but with often favourable prognosis. There is excess risk of KLS in first-degree relatives, suggesting a strong genetic contribution. So far, no mutation is identified in KLS and comprehensive genetic analysis of affected individuals is lacking. Here we performed whole genome single-nucleotide polymorphism (SNP) genotyping and exome sequencing in a large family with seven affected members...
|
| Psychometric properties of the Insomnia Severity Index in Ethiopian adults with substance use problems. | |
|
|
