Introduction: The prevalence of sleepy driving and sleep-related accidents (SRA) varies widely, and no data exist regarding the prevalence of sleepy driving in Saudi Arabia. Therefore, this study was designed to determine the prevalence and predictors of sleepy driving, near-misses, and SRA among drivers in Saudi Arabia...

Recent scientific evidences have brought a paradigm shift in our approach towards the concepts of insomnia and its management. The differentiation between primary and secondary insomnia was proved more hypothetical than actual and based upon the current evidences insomnia subtypes described in earlier system have been...

Sleep in humans can be broadly divided into non-rapid- eye-movement (NREM) and rapid-eye- movement (REM) sleep. NREM sleep is further divided into three stages: These range from the lightest sleep in stage N1 to the deepest level of sleep in stage N3 (referred to as slow-wave sleep or SWS)...

Definition:The class of sleep disorders known as parasomnias (L. para = next to; somnus = sleep) includes some of the most unusual, challenging, fascinating, and potentially instructive of all behavioral disorders. These are clinical disorders characterized by acute, abnormal behavioral or physiological events, exaggerated by sleep...

To the Editor: We read with interest the article by Lindenauer et al¹ in CHEST (May 2014), who retrospectively reported the outcome of patients hospitalized with pneumonia who had coexisting OSA. The study showed higher initial rates of mechanical ventilation,...

Sodium oxybate (SXB; Xyrem^®) is the sodium salt of gamma hydroxybutyric acid (GHB). SXB has been approved in the United States for the treatment of cataplexy and excessive daytime sleepiness (EDS) in patients with narcolepsy and in the European Union for the treatment of narcolepsy with cataplexy...

The role of the melatonin in relation with circadian rhythms and the sleep/wake cycle is well established. It is thought to play a role in controlling the sleep–wake cycle through physiological processes regulated in the suprachiasmatic nucleus of the hypothalamus...

Background: Sleep–wake disturbances have frequently been reported in bipolar disorder and schizophrenia, and are considered to be caused by an underlying circadian rhythm disorder...

IL-17 is a pro-inflammatory mediator that is believed to play a critical role in regulating tissue inflammation during asthma, COPD, as well as other inflammatory disorders. The level of expression of IL-17 has been shown to be upregulated in lung bronchial tissue of asthmatic patients...

Sleep disruption is one of the most challenging problems occurring with advancing age and additionally represents the most frequently expressed health complaint among the elderly (Monjan, 2007). Despite the ubiquity of the problem in modern times, disturbed sleep may not have always been a significant health problem, and...

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